任丽,理学博士,副教授。研究方向主要包括食源活性物质调节机体内分泌、代谢机制及对特定疾病的营养干预;递送体系的构建与应用;蛋白酶抑制剂及光学成像探针开发;白血病协同免疫治疗。
以第一/通讯作者在Food Chemistry、Critical Reviews in Food Science and Nutrition、Journal of Biological Chemistry、Phytomedicine、ACS Applied Materials & Interfaces、Food and Chemical Toxicology、Food & Function等期刊发表中科院一二区论文近20篇,1篇入选ESI热点论文。担任Theranostics、Biomedicine & Pharmacotherapy等期刊审稿人。主讲《食品免疫学》、《食品毒理学》等课程。
邮箱:liren77@jlu.edu.cn
办公室:永利总站线路检测和平校区ylzzcom永利总站线路检测508室
教育经历
2013.11–2016.04 俄亥俄州立大学Wexner医学中心, 内科医学部,免疫学专业,联合培养博士
2011.09–2016.06 吉林董事长命科学学院,分子酶学工程教育部重点实验室,细胞生物学专业,博士
2007.09–2010.06 吉林农业董事长命科学学院,生物技术专业, 硕士
2003.09–2007.06 吉林农业董事长命科学学院,生物技术专业, 理学学士
工作经历
2020.09–至今 永利总站线路检测,ylzzcom永利总站线路检测,副教授/硕士生导师
2019.09–2020.09 ylzzcom永利总站线路检测,讲师
2016.09–2019.09 永利总站线路检测无机合成与制备化学国家重点实验室,团队博士后
主持或参加科研项目(课题)情况
1. 吉林省教育厅“十三五”科学技术项目,增强白血病药物疗效的肠道微生物的鉴定及免疫调控机制研究,2019-2020,已结题,主持。
2. 中国博士后科学基金面上项目,二氧化硅纳米载药体系的构建及抗白血病耐药机制研究,2018-2019,已结题,主持。
3. 国家自然科学基金面上项目,膜型基质金属蛋白酶靶向多肽探针在肿瘤影像中的研究,2014-2017,已结题,第一参加人。
4. 企业技术开发委托,横向,开发改善慢性腹泻的新型益生菌饮品(3R119H124071),在研,主持。
近两年代表作
1. Jie Zhang, Petr Pavek, Rajamanikkam Kamaraj, Li Ren*, Tiehua Zhang*. Dietary phytochemicals as modulators of human pregnane X receptor. Critical Reviews in Food Science and Nutrition, Published online: 26 Oct 2021. (1区IF=11.208)
2. Haoyang Zou, Haiqing Ye, Jie Zhang*, Li Ren*. Recent advances in nuclear receptors-mediated health benefits of blueberry. Phytomedicine, 2022, 100: 154063. (1区IF=6.656)
3. Peiyu Xue, Guangjie Zhang, Jie Zhang*, Li Ren*. Synergism of ellagic acid in combination with radiotherapy and chemotherapy for cancer treatment. Phytomedicine, 2022, 99: 153998. (1区IF=6.656)
4. Peiyu Xue#, Guangjie Zhang#, Hongmei Zhao, Wencheng Wang, Jie Zhang*, Li Ren*. Serum albumin complexed with ellagic acid from pomegranate peel and its metabolite urolithin B. Food Bioscience, 2022, 46: 101618. (2区IF=5.318)
5. Li Ren, Jie Zhang*, Tiehua Zhang*. Immunomodulatory activities of polysaccharides from Ganoderma on immune effector cells. Food Chemistry, 2021, 340: 127933. (1区IF=9.231) ESI热点论文
6. Jie Zhang, Jiarui Zhao, Yantong Sun, Yuan Liang, Jingqi Zhao, Haoyang Zou, Tiehua Zhang, Li Ren*. GR-mediated anti-inflammation of α-boswellic acid: Insights from in vitro and in silico studies. Food and Chemical Toxicology, 2021, 155: 112379. (1区IF=5.572)
7. Li Ren, Shu Niu, Yantong Sun, Yuan Liang, Jingqi Zhao, Tiehua Zhang, Jie Zhang*. Anti-inflammatory action of betulin and its potential as a dissociated glucocorticoid receptor modulator. Food and Chemical Toxicology, 2021, 157: 112539. (1区IF=5.572)
8. Tianzhu Guan#, Guangjie Zhang#, Yantong Sun, Jie Zhang*, Li Ren*. Preparation, characterization, and evaluation of HP-β-CD inclusion complex with alcohol extractives from star anise. Food & Function, 2021, 12(20): 10008-10022. (2区IF=6.317)
9. Yuan Liang, Tiehua Zhang, Jingqi Zhao, Chenfei Li, Haoyang Zou, Fangyu Li, Jie Zhang*, Li Ren*. Glucocorticoid receptor-mediated alleviation of inflammation by berberine: in vitro, in silico and in vivo investigations. Food & Function, 2021, 12(23): 11974-11986. (2区IF=6.317)
10. Yuan Liang, Tiehua Zhang, Yantong Sun, Mengxue Diao, Jie Zhang*, Li Ren*. Multi-spectroscopic and molecular modeling studies on the interactions of serum albumin with 20(S, R)-protopanaxadiol and 20(S, R)-protopanaxatriol that inhibit HCT-116 cells proliferation. Food Bioscience, 2021, 40: 100913. (2区IF=5.318)